منابع مشابه
Antifungal photodynamic therapy.
In photodynamic antimicrobial chemotherapy (PACT), a combination of a sensitising drug and visible light causes selective destruction of microbial cells. The ability of light-drug combinations to kill microorganisms has been known for over 100 years. However, it is only recently with the beginning of the search for alternative treatments for antibiotic-resistant pathogens that the phenomenon ha...
متن کاملPhotodynamic therapy (PDT)
Photodynamic therapy (PDT) is a comparatively novel therapeutic method involving a safe light source and a light-sensitive substance, termed as photosensitizers (PSs), such as methylene blue (MB), toluidine blue (TBO), sulfonated aluminum phthalocyanine, chlorine derivatives, nontoxic indocyanine green (ICG), and curcumin (CUR). (1) The combination of a nontoxic PS with low-intensity visible li...
متن کاملConcepts and Principles of Photodynamic Therapy as an Alternative Antifungal Discovery Platform
Opportunistic fungal pathogens may cause superficial or serious invasive infections, especially in immunocompromised and debilitated patients. Invasive mycoses represent an exponentially growing threat for human health due to a combination of slow diagnosis and the existence of relatively few classes of available and effective antifungal drugs. Therefore systemic fungal infections result in hig...
متن کاملPhotodynamic Inactivation of Endopathogenic Microbiota Using Curcumin- mediated Antimicrobial Photodynamic Therapy
Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...
متن کاملPhotodynamic Therapy Authors:
Rufino Silva, MD, PhD Centro Hospitalar e Universitário de Coimbra (CHUC). Coimbra, Portugal Faculty of Medicine, University of Coimbra. Portugal (FMUC) Association for Innovation and Biomedical Research on Light and Image (AIBILI). Coimbra. Portugal Introduction Photodynamic therapy was approved in 2000 as an alternative treatment for patients with AMD of the exudative form, having been the fi...
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ژورنال
عنوان ژورنال: Microbiological Research
سال: 2008
ISSN: 0944-5013
DOI: 10.1016/j.micres.2007.08.001